Asacol is a digestive health / gastro health pill from the pharma company Procter & Gamble and a popular medicine among people with digestive problems since many years.

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Asacol, also known by its generic name mesalamine, is a medication commonly used in the treatment of inflammatory bowel diseases (IBD), particularly ulcerative colitis. This medication belongs to a class of drugs called aminosalicylates, which are designed to reduce inflammation in the gastrointestinal tract.

Key Uses of Asacol:

  1. Ulcerative Colitis: Asacol is often prescribed to individuals with ulcerative colitis, a chronic inflammatory condition that affects the colon (large intestine). It helps to alleviate symptoms such as abdominal pain, diarrhea, and rectal bleeding associated with this condition.

  2. Crohn’s Disease: In some cases, mesalamine-based medications like Asacol may be used to treat mild to moderate cases of Crohn’s disease, another form of IBD that can affect any part of the digestive tract.

How Asacol Works:

The exact mechanism of how Asacol works isn’t fully understood, but it’s believed to exert its anti-inflammatory effects directly in the colon’s lining. By reducing inflammation, it helps to control symptoms and promote periods of remission in patients with ulcerative colitis and, in some cases, Crohn’s disease.

Forms of Asacol:

Asacol is available in various formulations, including tablets, delayed-release tablets, and rectal suppositories or enemas. The choice of formulation depends on the location and severity of the inflammation in the digestive tract.

  • Oral Tablets: Oral Asacol tablets are typically taken by mouth and designed to release mesalamine in the small intestine and colon to treat inflammation throughout the gastrointestinal tract.

  • Delayed-Release Tablets: These tablets are designed to release mesalamine in the colon specifically, making them suitable for patients with colonic inflammation.

  • Rectal Suppositories/Enemas: For patients with inflammation in the rectum and lower colon, rectal formulations such as suppositories and enemas are available. These deliver the medication directly to the affected area.

Side Effects and Precautions:

While Asacol is generally well-tolerated, some individuals may experience side effects, including headache, nausea, abdominal pain, or diarrhea. In rare cases, serious allergic reactions can occur.

Before starting Asacol, it’s important to inform your healthcare provider of any existing medical conditions, allergies, or medications you’re currently taking. They will assess whether Asacol is suitable for your specific case and provide guidance on dosing and potential side effects.


Asacol, or mesalamine, is an essential medication for managing the symptoms and inflammation associated with ulcerative colitis and, in some cases, Crohn’s disease. It helps individuals with these conditions achieve and maintain periods of remission and improved quality of life. If you have been prescribed Asacol or are considering it as a treatment option, it’s crucial to work closely with your healthcare provider to ensure it’s the right choice for your particular situation and to receive proper guidance on its usage.

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